
Nettle by Samphire Neuroscience is transforming the way menstrual pain and mood symptoms are managed through cutting-edge neuromodulation technology. This non-invasive, wearable headband uses transcranial direct current stimulation (tDCS) to target the motor cortex and dorsolateral prefrontal cortex—two key areas involved in pain perception and emotional regulation. By gently modulating brain activity, Nettle helps reduce period-related pain and improve mood, providing a safe and effective alternative to medication.
Clinically validated and CE-marked as a Class IIa medical device, Nettle has been rigorously tested for safety and efficacy. Studies show that 72% of users experience significant pain relief, while 67% report improved mood symptoms after just one month of use. Its use is now being trialled in endometriosis with the NHS and PMDD with Queen Mary University London. The treatment involves five 20-minute sessions per cycle in the days leading up to menstruation, making it easy to integrate into daily routines.
Designed for at-home use, Nettle is powered by a rechargeable battery and seamlessly controlled via a mobile app, ensuring a convenient and user-friendly experience. With its strong scientific foundation and commitment to improving women’s health, Nettle is redefining menstrual care—offering targeted relief and empowerment to those who need it most.