Samphire Neuroscience: Redefining women’s health with brain-based wearables
Find out how Samphire Neuroscience is tackling menstrual pain and emotional symptoms by targeting our brain circuits, and how being a Fellow has helped scale their innovation.
For decades, treatment options for menstrual pain and emotional symptoms have been limited to painkillers or hormones – solutions that don’t work for everyone and often bring side effects of their own. Samphire Neuroscience is changing that with Nettle™, the first EU-cleared neuromodulation device designed specifically for women’s health. Non-invasive, drug-free, and hormone-free, Nettle targets the brain circuits responsible for pain and mood regulation, offering a new level of control and relief for women living with premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), endometriosis, and beyond.
What is Nettle and what problem does it solve?
Nettle™ is a discreet, wearable device that brings neuroscience directly into women’s daily lives. By modulating brain activity linked to pain and mood, it provides relief without the drawbacks of medication or hormones.
For too long, women’s health conditions have been underserved, leaving patients with few options. Nettle offers an alternative – accessible, evidence-based, and tailored to women’s needs – that empowers women to manage their health on their own terms.
What was your inspiration and motivation?
The founder’s inspiration came from recognising a deep imbalance in healthcare research and innovation.
“The lack of progress in women’s health was striking to me. Conditions like PMS, PMDD, and endometriosis affect hundreds of millions worldwide, yet remain under-researched and underserved. As a neuroscientist, I knew the brain was central to these experiences of pain and mood. What motivates me is turning neuroscience into solutions that let women live with more control, without relying on drugs or hormones.”
Dr Emilė Radytė, Co-Founder and CEO, Nettle (Samphire Neuroscience)
The drive to apply cutting-edge neuroscience to an area too often overlooked, sits at the core of Samphire’s mission.
Why did you become a Fellow?
Becoming part of the NHS Innovation Accelerator (NIA) marked a milestone for Samphire Neuroscience. For the team, it’s more than recognition, it’s a gateway to impact.
“It’s a privilege. Being part of the NIA opens doors to NHS partnerships, expert networks, and a community of innovators navigating the same challenges of scaling impact in healthcare. For me, it’s also recognition that women’s health belongs at the heart of innovation, not at the margins.”
Through the fellowship, Samphire gains the platform and support needed to integrate Nettle into clinical pathways and broaden access for patients across the UK.
Looking ahead
Samphire’s vision extends far beyond a single device.
“In five years time, I hope Samphire has built a whole set of women’s health medical devices – with Nettle as the first in a pipeline tackling menstrual, hormonal, and chronic pain conditions. The Samphire app will grow from a companion tool into a true hub for personalised, data-driven care.”
The ambition is to create not just products, but an ecosystem of solutions for women’s health.
Want to find out more? Visit the innovation page where you can contact the innovator directly, or check out their website.
